Gut Microbiota Differences in Children From Distinct Socioeconomic Levels Living in the Same Urban Area in Brazil/Experiment 1
From BugSigDB
Reviewed Marked as Reviewed by Claregrieve1 on 2022/12/31
Curated date: 2022/07/11
Curator: Kaluifeanyi101
Revision editor(s): Kaluifeanyi101, Claregrieve1, Victoria
Subjects
- Location of subjects
- Brazil
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Socioeconomic status class,Socioeconomic status,socioeconomic status,socioeconomic factors
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Private school children (High SES)
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Children living in slum (Low SES)
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Children between 5 and 11 years old living in slums in Sao Paulo State, Brazil.
- Group 0 sample size Number of subjects in the control (unexposed) group
- 30
- Group 1 sample size Number of subjects in the case (exposed) group
- 100
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 1 month
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- RT-qPCR
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Mann-Whitney (Wilcoxon)
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
Signature 1
Reviewed Marked as Reviewed by Claregrieve1 on 2022/12/31
Source: Table 3
Description: Differential microbial abundance between the slum children and children from the private school
Abundance in Group 1: increased abundance in Children living in slum (Low SES)
| NCBI | Quality Control | Links |
|---|---|---|
| Escherichia coli | ||
| Eubacterium | ||
| Bacillota | ||
| Lactobacillus sp. | ||
| Methanobrevibacter smithii | ||
| unclassified Bacteroidota |
Revision editor(s): Kaluifeanyi101, Claregrieve1
Signature 2
Reviewed Marked as Reviewed by Claregrieve1 on 2022/12/31
Source: Table 3
Description: Differential microbial abundance between the slum children and children from the private school
Abundance in Group 1: decreased abundance in Children living in slum (Low SES)
| NCBI | Quality Control | Links |
|---|---|---|
| Clostridioides difficile | ||
| Clostridium perfringens | ||
| Salmonella sp. |
Revision editor(s): Kaluifeanyi101, Claregrieve1
