Profiling the Salivary microbiome of the Qatari population/Experiment 8

From BugSigDB


Reviewed Marked as Reviewed by Atrayees on 2023-6-23

Curated date: 2023/03/31

Curator: Suwaiba

Revision editor(s): Suwaiba, Atrayees, LGeistlinger

Subjects

Location of subjects
Qatar
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Saliva Sailva normalis,Saliva atomaris,Saliva molecularis,Salivary gland secretion,Saliva,saliva
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Tea consumption measurement Tea consumption measurement,tea consumption measurement
Group 0 name Corresponds to the control (unexposed) group for case-control studies
Non tea drinkers
Group 1 name Corresponds to the case (exposed) group for case-control studies
Tea drinkers
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Participants considered tea drinkers
Group 0 sample size Number of subjects in the control (unexposed) group
229
Group 1 sample size Number of subjects in the case (exposed) group
768

Lab analysis

Sequencing type
16S
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
V1-V3
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
LEfSe
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
2
LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
2

Alpha Diversity

Shannon Estimator of species richness and species evenness: more weight on species richness
increased
Chao1 Abundance-based estimator of species richness
increased
Simpson Estimator of species richness and species evenness: more weight on species evenness
increased
Richness Number of species
increased

Signature 1

Reviewed Marked as Reviewed by Atrayees on 2023-6-20

Curated date: 2023/03/31

Curator: Suwaiba

Revision editor(s): Suwaiba

Source: Figure 8c

Description: Graphs of linear discriminant analysis (LDA) scores for differentially abundant bacterial phyla and genera; among the two groups. Features with LDA scores ≥ 2 are presented

Abundance in Group 1: decreased abundance in Tea drinkers

NCBI Quality ControlLinks
Capnocytophaga

Revision editor(s): Suwaiba