Interplay between bladder microbiota and overactive bladder symptom severity: a cross-sectional study
- Location of subjects
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Mild Overactive Bladder
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Moderate/Severe Overactive Bladder
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Adult patients with Overactive Bladder Symptom Score greater than five (OABSS > 5).
- Group 0 sample size Number of subjects in the control (unexposed) group
- Group 1 sample size Number of subjects in the case (exposed) group
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 4 weeks
- Sequencing type
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
- Matched on Factors on which subjects have been matched on in a case-control study
- age, hypertension, race, body mass index
- Pielou Quantifies how equal the community is numerically
- Shannon Estimator of species richness and species evenness: more weight on species richness
- Chao1 Abundance-based estimator of species richness
- Simpson Estimator of species richness and species evenness: more weight on species evenness
- Richness Number of species
Source: Table 2
Description: Increased abundance of bacteria in moderate/severe overactive bladder patients.
Abundance in Group 1: increased abundance in Moderate/Severe Overactive Bladder
Source: Table 2
Description: Decreased abundance of bacteria in moderate/severe overactive bladder patients.
Abundance in Group 1: decreased abundance in Moderate/Severe Overactive Bladder
Revision editor(s): Deacme