Efficacy of fecal microbiota transplantation in 2 children with recurrent Clostridium difficile infection and its impact on their growth and gut microbiome/Experiment 1
From BugSigDB
Subjects
- Location of subjects
- United States of America
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Clostridium difficile infection clostridium difficile disease,Clostridium difficile infection,clostridium difficile infection
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Children with recurrent Clostridium difficile Infection
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- Efficacy of Fecal Microbiota Transplantation on Children with Recurrent Clostridium difficile Infection.
- Group 1 sample size Number of subjects in the case (exposed) group
- 2
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- Not specified
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Confounders controlled for Confounding factors that have been accounted for by stratification or model adjustment
- age, cesarean section, premature birth, antibiotic exposure
Alpha Diversity
- Shannon Estimator of species richness and species evenness: more weight on species richness
- increased
Signature 1
Source: Figure 2b
Description: Histograms showing relative abundances of microbiota members at the taxonomic phylum level.
Abundance in Group 1: increased abundance in Children with recurrent Clostridium difficile Infection
| NCBI | Quality Control | Links |
|---|---|---|
| Bacteroidota |
Revision editor(s): Victoria
Signature 2
Source: Figure 2b
Description: Histograms showing relative abundances of microbiota members at the taxonomic phylum level.
Abundance in Group 1: decreased abundance in Children with recurrent Clostridium difficile Infection
| NCBI | Quality Control | Links |
|---|---|---|
| Bacillota | ||
| Pseudomonadota | ||
| Verrucomicrobiota | ||
| Actinomycetota |
Revision editor(s): Victoria
