Establishment of a non-Westernized gut microbiota in men who have sex with men is associated with sexual practices/Experiment 11

From BugSigDB


Reviewed Marked as Reviewed by Svetlana up on 2024-5-2

Curated date: 2024/04/17

Curator: MyleeeA

Revision editor(s): MyleeeA

Subjects

Location of subjects
China
Germany
Host species Species from which microbiome was sampled. Contact us to have more species added.
Homo sapiens
Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
Feces Cow dung,Cow pat,Droppings,Dung,Excrement,Excreta,Faeces,Fecal material,Fecal matter,Fewmet,Frass,Guano,Matières fécales@fr,Merde@fr,Ordure,Partie de la merde@fr,Piece of shit,Porción de mierda@es,Portion of dung,Portion of excrement,Portion of faeces,Portion of fecal material,Portion of fecal matter,Portion of feces,Portion of guano,Portion of scat,Portionem cacas,Scat,Spoor,Spraint,Stool,Teil der fäkalien@de,Feces,feces
Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
Male homosexuality Male homosexuality,male homosexuality
Group 0 name Corresponds to the control (unexposed) group for case-control studies
MSM
Group 1 name Corresponds to the case (exposed) group for case-control studies
Non Westernized
Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
Non-Westernized describes a population practicing a traditional lifestyle relating to factors such as diet, hygiene, and with limited access to modern medical healthcare and pharmaceuticals (e.g., antibiotics).
Group 0 sample size Number of subjects in the control (unexposed) group
93
Group 1 sample size Number of subjects in the case (exposed) group
481
Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
6 Months

Lab analysis

Sequencing type
WMS
16S variable region One or more hypervariable region(s) of the bacterial 16S gene
Not specified
Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
Illumina

Statistical Analysis

Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
relative abundances
Statistical test
Fisher's Exact Test
Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
0.05
MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
Yes


Signature 1

Reviewed Marked as Reviewed by Svetlana up on 2024-5-2

Curated date: 2024/04/18

Curator: MyleeeA

Revision editor(s): MyleeeA

Source: Supplementary Table S3

Description: Species enriched in MSM and Non Westernized.

Abundance in Group 1: increased abundance in Non Westernized

NCBI Quality ControlLinks
Anaerotruncus massiliensis (ex Liu et al. 2021)
Angelakisella massiliensis
Bacteroides salyersiae
Bifidobacterium catenulatum
Brachyspira pilosicoli
Butyricimonas
Candidatus Alangreenwoodia gallinarii
Candidatus Allobutyricicoccus pentlandensis
Candidatus Allochristensenella caecavium
Candidatus Avimonas narfae
Candidatus Geddesella stercoravicola
Candidatus Metalachnospira gallinarum
Candidatus Neochristensenella gallicola
Candidatus Neoruminococcus faecicola
Candidatus Pseudolachnospira avium
Clostridia bacterium
Clostridiaceae bacterium
Clostridiales bacterium
Clostridium sp.
Coprobacter fastidiosus
Eisenbergiella tayi
Erysipelotrichaceae bacterium
Eubacterium sp.
Flavonifractor sp.
Holdemania filiformis
Hydrogeniiclostridium mannosilyticum
Intestinimonas massiliensis (ex Afouda et al. 2020)
Intestinimonas timonensis
Lachnoclostridium sp.
Lachnospiraceae bacterium
Massiliimalia timonensis
Megasphaera elsdenii
Merdimmobilis hominis
Merdimonas faecis
Oscillibacter sp.
Phocaeicola vulgatus
Prevotella bivia
Propionibacterium freudenreichii
Rothia mucilaginosa
Sanguibacteroides justesenii
unclassified Oscillospiraceae
Oscillospiraceae bacterium
Massilimicrobiota sp.

Revision editor(s): MyleeeA

Signature 2

Reviewed Marked as Reviewed by Svetlana up on 2024-5-2

Curated date: 2024/04/19

Curator: MyleeeA

Revision editor(s): MyleeeA

Source: Supplementary Table S3

Description: Species enriched in MSM and Non Westernized.

Abundance in Group 1: decreased abundance in Non Westernized

NCBI Quality ControlLinks
Actinomyces sp.
Bacteroidaceae bacterium
Prevotellamassilia timonensis
Segatella copri clade CSegatella copri clade C
Prevotella sp.
Candidatus Gastranaerophilales bacterium
TM7 phylum sp. oral taxon 348
Candidatus Nanosynsacchari sp. TM7_ANC_38.39_G1_1
Elusimicrobiales bacterium
Bacilli bacterium
unclassified Bacilli
Leuconostoc
Lactococcus petauri
Lactococcus plantarum
Streptococcus sp.
Clostridia bacterium
unclassified Clostridia
Clostridium disporicum
Clostridium sp.
Mogibacterium diversum
Eubacteriaceae bacterium
Blautia
Blautia faecis
Coprococcus catus
Lachnospiraceae bacterium
unclassified Lachnospiraceae
Lachnospira eligens
[Ruminococcus] lactaris
Roseburia sp.
Oscillospiraceae bacterium
unclassified Oscillospiraceae
Ruminococcus bicirculans (ex Liu et al. 2021)
Erysipelotrichaceae bacterium
Selenomonas
Veillonella parvula
Veillonella rogosae
Lentisphaeria bacterium
Escherichia marmotae
Spirochaetia bacterium

Revision editor(s): MyleeeA