Mycobiome Study Reveals Different Pathogens of Vulvovaginal Candidiasis Shape Characteristic Vaginal Bacteriome/Experiment 5
From BugSigDB
Needs review
Subjects
- Location of subjects
- China
- Host species Species from which microbiome was sampled. Contact us to have more species added.
- Homo sapiens
- Body site Anatomical site where microbial samples were extracted from according to the Uber Anatomy Ontology
- Vagina Distal oviductal region,Distal portion of oviduct,Vaginae,Vagina,vagina
- Condition The experimental condition / phenotype studied according to the Experimental Factor Ontology
- Female reproductive system disease disease of female genital system,disease of female reproductive system,disease or disorder of female reproductive system,disorder of female genital system,disorder of female genital tract,disorder of female reproductive system,female reproductive disease,female reproductive system disease,female reproductive system disease or disorder,female reproductive system disorder,gynecological disease,Female reproductive system disease
- Group 0 name Corresponds to the control (unexposed) group for case-control studies
- Other reproductive tracts Infection (RTI) subjects
- Group 1 name Corresponds to the case (exposed) group for case-control studies
- Healthy Controls
- Group 1 definition Diagnostic criteria applied to define the specific condition / phenotype represented in the case (exposed) group
- The participants in this group were healthy women
- Group 0 sample size Number of subjects in the control (unexposed) group
- 114
- Group 1 sample size Number of subjects in the case (exposed) group
- 47
- Antibiotics exclusion Number of days without antibiotics usage (if applicable) and other antibiotics-related criteria used to exclude participants (if any)
- 1 month
Lab analysis
- Sequencing type
- 16S
- 16S variable region One or more hypervariable region(s) of the bacterial 16S gene
- V1-V2
- Sequencing platform Manufacturer and experimental platform used for quantifying microbial abundance
- Illumina
Statistical Analysis
- Data transformation Data transformation applied to microbial abundance measurements prior to differential abundance testing (if any).
- relative abundances
- Statistical test
- LEfSe
- Significance threshold p-value or FDR threshold used for differential abundance testing (if any)
- 0.05
- MHT correction Have statistical tests be corrected for multiple hypothesis testing (MHT)?
- No
- LDA Score above Threshold for the linear discriminant analysis (LDA) score for studies using the popular LEfSe tool
- 2.0
Signature 1
Needs review
Source: Figure 4
Description: Differentially abundant taxa between three RTIs and healthy control groups
Abundance in Group 1: increased abundance in Healthy Controls
| NCBI | Quality Control | Links |
|---|---|---|
| Lactobacillus | ||
| Streptococcus anginosus |
Revision editor(s): Aleru Divine
