The Urinary Microbiome in Women Using Single-Use Versus Reusable Catheters for Intermittent Catheterization: An Exploratory Substudy of the COMPaRE Trial/Experiment 1/Signature 1
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< The Urinary Microbiome in Women Using Single-Use Versus Reusable Catheters for Intermittent Catheterization: An Exploratory Substudy of the COMPaRE Trial | The Urinary Microbiome in Women Using Single-Use Versus Reusable Catheters for Intermittent Catheterization: An Exploratory Substudy of the COMPaRE Trial/Experiment 1
Source: Figure 5
Description: Opportunistic bacterial taxa significantly increased in women using reusable versus single-use catheters for clean intermittent self-catheterization. Veillonella, while found in healthy urinary microbiomes, has been associated with bladder cancer and stress urinary incontinence in other studies. Finegoldia magna, commonly detected in asymptomatic women, has been linked to worsening urinary symptoms before pelvic surgery. Study involved 28 female patients (67.9% neurogenic dysfunction) with 6-week follow-up, analyzed by 16S rRNA sequencing and DESeq2 differential abundance analysis (p<0.01).
Abundance in Group 1: increased abundance in Intervention arm / Reusable group
| NCBI | Quality Control | Links |
|---|---|---|
| Veillonella (p < 0.001)Veillonella (p < 0.001) | ||
| Finegoldia (p < 0.001)Finegoldia (p < 0.001) |
Revision editor(s): Martha KJ
