The Urinary Microbiome in Women Using Single-Use Versus Reusable Catheters for Intermittent Catheterization: An Exploratory Substudy of the COMPaRE Trial/Experiment 1/Signature 2
Source: Figure 5
Description: Potential uropathogens significantly reduced in women transitioning to reusable catheters for clean intermittent self-catheterization. Escherichia-Shigella, the most abundant genus overall (36.3% prevalence), and Aerococcus both showed marked decreases, potentially indicating reduced urinary tract infection risk. However, the paper notes that E. coli presence may not be a reliable UTI predictor, as infections are influenced more by overall microbiome composition than specific pathogens. No significant difference in actual UTI rates was observed between groups during the study period. Study involved 28 female patients with neurogenic/non-neurogenic urinary retention, 6-week randomized controlled design.
Abundance in Group 1: decreased abundance in Intervention arm / Reusable group
| NCBI | Quality Control | Links |
|---|---|---|
| Aerococcus (p < 0.001)Aerococcus (p < 0.001) | ||
| Escherichia-Shigella (p < 0.001)Escherichia-Shigella (p < 0.001) |
Revision editor(s): Martha KJ
