Graves disease

From BugSigDB


A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes ( GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
Aliases
  • Basedow disease
  • Basedow disease
  • Basedow's disease
  • Basedow's disease
  • exophthalmic goiter
  • Flajani-Basedow-Graves disease
  • grave's disease
  • Graves disease
  • Graves disease
  • Graves' disease
  • Graves' disease
  • Graves' hyperthyroidism
  • parry disease
  • toxic diffuse goiter