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<strong>BugSigDB: A Comprehensive Database of Published Microbial Signatures</strong>
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<h1 class="border-0 font-weight-bold mb-4">BugSigDB</h1>
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A Comprehensive Database of Published Microbial Signatures
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Please check out the functionality being developed for the future main page: https://bugsigdb.org/Project:Dynamic_Main_Page
BugSigDB.org (published in '''[https://www.nature.com/articles/s41587-023-01872-y Nature Biotechnology''']) is a community-editable [https://www.semantic-mediawiki.org Semantic Mediawiki knowledge management system]. Its primary functions include '''1. standardization''' of key elements of published microbiome studies using ontologies and the NCBI taxonomy, '''2. [https://bugsigdb.org/Special:RunQuery/Drill?Drill%5BCondition%20logic%5D=AND&Drill%5BLocation%20logic%5D=AND&Drill%5BSite%20logic%5D=AND&_run=1 searchability]''', '''3. Enrichment Analysis''' using [[Help:Export|bulk exports]], [https://github.com/waldronlab/BugSigDBExports GMT files], or other software (e.g. [https://bioconductor.org/packages/bugsigdbr/ bugsigdbr]), and '''4. community interaction:''' you can [[Special:RequestAccount|request an account]], [[Help:Contents|contribute or analyze]], learn [[Project:About|about]] the project, [https://github.com/waldronlab/BugSigDB/issues report issues], and ask questions on the [https://community-bioc.slack.com/archives/C04RATV9VCY/p1697144958544289 #bugsigdb channel] of the [https://slack.bioconductor.org/ community-bioc Slack team]. This collaborative effort aims to accelerate microbiome research by providing a comprehensive database of microbial signatures from published studies, along with relevant information on study design and geography, health outcomes, host body site, and experimental methods.


For R access see https://github.com/waldronlab/bugsigdbr
[[Project:About|<span class="mw-ui-button mw-ui-progressive float-right mt-3">About this project</span>]]
 
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BugSigDB under active development and not yet "officially" released, so this front page is a placeholder.
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{{Random taxon}}{{Random study|2}}
BugSigDb is a manually curated database of microbial signatures from the published literature of differential abundance studies of human and other host microbiomes. BugSigDB provides:
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* standardized data on geography, health outcomes, host body sites, and experimental, epidemiological, and statistical methods using controlled vocabulary,
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* results on microbial diversity,
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* microbial signatures standardized to the NCBI taxonomy, and
<div class="card-body d-flex align-items-center justify-content-between"><small>Fuzzy {{!}} Parameterized {{!}} Logical operators &raquo; {{#queryformlink: form=Drill
* identification of published signatures where a microbe has been reported.
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  |Drill[Condition logic]=AND
You can contribute the results of your study to take advantage of automated analyses and interpretation in the context of the published literature. For an example of a study with extensive data, see [[Study 1|The gut microbiota in conventional and serrated precursors of colorectal cancer]].
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  |Drill[Site logic]=AND
See the [[Help:Contents|Help page]] for help for users, contributors / curators, reviewers, and administrators. For questions, feedback, collaborations, please post a message at https://www.github.com/waldronlab/bugsigdb/discussions.
  |Drill[Condition]=~*cancer*
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<div class="card-header text-secondary px-3 py-2 font-weight-bold">Statistics</div>
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{{MediaWiki:Statistics-footer}}
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<div class="card-footer py-2">{{#queryformlink: form=Drilldown|link text=<span class="mw-ui-button mw-ui-quiet text-primary pl-0 pr-1">Browse all studies</span>|_run=1}} <small>by Host species {{!}} Body site {{!}} Condition {{!}} Taxa {{!}} Location of subjects.</small>
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<div class="card-header font-weight-bold">Top 5 Contributors in the last 30 days</div>
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{{Special:ContributionScores/5/30/notools}}
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<div class="card-footer py-2">[[Special:ContributionScores|<span class="mw-ui-button mw-ui-quiet text-primary pl-0 pr-1">Extended Statistics</span>]]</div>
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Latest revision as of 14:32, 21 February 2024

BugSigDB

A Comprehensive Database of Published Microbial Signatures

BugSigDB.org (published in Nature Biotechnology) is a community-editable Semantic Mediawiki knowledge management system. Its primary functions include 1. standardization of key elements of published microbiome studies using ontologies and the NCBI taxonomy, 2. searchability, 3. Enrichment Analysis using bulk exports, GMT files, or other software (e.g. bugsigdbr), and 4. community interaction: you can request an account, contribute or analyze, learn about the project, report issues, and ask questions on the #bugsigdb channel of the community-bioc Slack team. This collaborative effort aims to accelerate microbiome research by providing a comprehensive database of microbial signatures from published studies, along with relevant information on study design and geography, health outcomes, host body site, and experimental methods.

About this project

NCBI.png 1573535Featured Taxon
Holdemanella(genus)
BugSigDB Statistics
  • Number of studies: 38 (filter)
  • Number of signatures: 53
  • Number of direct descendants: 3
Study by nameFeatured Studies
Association of dietary fibre intake and gut microbiota in adults
The British journal of nutrition, 2018 | Feces | Diet | United States of America

Taxa
Please enter 1 or more characters.

Fuzzy | Parameterized | Logical operators » ExampleAdvanced Search
Statistics
  • 1399 studies
  • 7582 signatures
  • 2195 unique taxa
  • 44 host species
  • 94 locations
  • 173 body sites
  • 518 conditions
  • contributed by 178 contributors
Top 5 Contributors in the last 30 days

Last 30 days (Top 5)